We can all see the Earth is heating up, that polar ice and glaciers are melting, and that ever more fires, floods and droughts are screaming at us that our climate is unraveling. Our societies are also showing signs of unraveling. But the legendary, world-renowned Native American Rights leader, Oren R. Lyons, Faithkeeper of the Turtle Clan of the Onondaga Nation, who, among countless achievements, helped establish the UN’s Working Group on Indigenous Populations and authored or co-authored such profoundly influential texts as: Wilderness in Native American Culture and Exiled in the Land of the Free: Democracy, Indian Nations and the U.S. Constitution, is here to tell us that we can’t give up. We have profound responsibilities to coming generations, and time is of the essence, but if we want to reverse course to prevent climate catastrophe and achieve real peace, we will have to dig deep to transform contemporary society’s core values that underlie and drive the existential crises we are facing. This keynote talk was delivered at the 2024 Bioneers Conference. To see other talks from the conference, visit http://www.bioneers.org/2024talks